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KMID : 0358819840110020161
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1984 Volume.11 No. 2 p.161 ~ p.168
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EXPERIMENTAL STUDY ON WOUND CONTRACTION IN SIALADENECTOMIZED RATS
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Minn Kyung-Won
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Abstract
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We have studied on wound contraction of full thickness open wounds in sialadenectomized rats.
Sialadenectomized rats(n=30) and controls(n=24) had excision of a standard sized rectangular full thickness skin and panniculus carnosus.
Rats without salivary glands showed a slower rate of wound contraction than controls (p＜0.001). However, this delay in wound contraction was abolished if sialadenectomized rats were caged with rats having intact salivary glands.
In conclusion, salivary glands contain a factor(s), largely applied by licking, which accelerate(s) early wound contraction.
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